top of page

Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice

Authors: Suliman-Lavie R; Title B; Cohen Y; Hamada N; Tal M; Tal N; Monderer-Rothkoff G; Gudmundsdottir B; Gudmundsson KO; Keller JR; Huang GJ; Nagata K-I; Yarom Y; Shifman S

Abstract

Brain-specific Pogz knockout mice show growth/microcephaly and behavioral phenotypes with broad transcriptional upregulation and altered cerebellar Purkinje cell physiology.

Global-Advocacy-Alliance-600px.png

Cure POGZ Disorders Foundation does not discriminate against race, color, religion, gender, sexual orientation, national origin, age, disability, gender identity and expression, marital or military status, or any class protected by applicable law.

  • Facebook
  • Instagram
  • LinkedIn
bottom of page