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Loss of POGZ alters neural differentiation of human embryonic stem cells

Authors: Deng L; Mojica-Perez SP; Azaria RD; Schultz M; Parent JM; Niu W

Abstract

CRISPR LoF in human ESCs reduces neural progenitor proliferation, perturbs migration in rosettes, and simplifies neuronal dendritic arbors in derived neurons.

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Cure POGZ Disorders Foundation does not discriminate against race, color, religion, gender, sexual orientation, national origin, age, disability, gender identity and expression, marital or military status, or any class protected by applicable law.

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